The Genetics & Molecular Components of Glioma Patients

Upon completion of this activity, participants should be able to:

  • Describe the histological classification of low and high-grad gliomas
  • Describe the role of IDH1, ARTRX, and 1p19q co-deletions, and MGMT and TERT promoter mutations on glioma growth
  • Recognize the significance of common molecular and genetic mutations on glioma response to chemoradiation and prognosis


AANS Member: Free | Non-member: $19

Shawn Hervey-Jumper, MD
University of Michigan
Ann Arbor, MI

Randy L. Jensen, MD, PhD, FAANS
University of Utah Health Care
Salt Lake City, UT

B. Gregory Thompson, MD, FAANS
University of Michigan
Ann Arbor, MI

Samantha Luebbering
American Association of Neurological Surgeons
Rolling Meadows, IL

The AANS controls the content and production of this CME activity and attempt to ensure the presentation of balanced, objective information. In accordance with the Standards for Commercial Support established by the Accreditation Council for Continuing Medical Education (ACCME), speakers, paper presenters/authors and staff (and the significant others of those mentioned) are asked to disclosed any relationship they or their co-authors have with commercial interests which may be relate to the content of their lecture.

The ACCME defines “relevant financial relationships” as financial relationships in any amount occurring within the past 12 months that create a conflict of interest. Relationship refers to receipt of royalties, consultantship, funding by research grant, receiving honoraria for education service elsewhere, or any other relationship to a commercial interest that provides sufficient reason for disclosure.

It is the policy of the AANS that all individuals in a position to affect the content of a CME activity disclose relationships that they or their spouse/partner have with commercial entities. Further, should any such relationship be determined to be in possible conflict of interest as it relates to the individual’s proposed role in the CME activity, such conflicts of interest will be resolved prior to confirmation of the individual’s participation.

All potential conflicts of interest have been reviewed by an effective peer review committee to ensure the content is valid and aligned with the interest of the activity audience.

Speakers, paper presenters/authors and staff (and the significant others of those mentioned) who have disclosed a relationship with commercial interests whose products may have a relevance to their presentation are listed below.

NameCompany NameRelationship Type
Randy L. Jensen, MD, PhD, FAANSMedtronic,Pharmokinesis, Varian, IMRISConsultants

Those who have reported they do not have any relationships with commercial interests:
Shawn Hervey-Jumper, MD
Samantha Luebbering
B. Gregory Thompson, MD, FAANS

The opinions expressed in this educational activity are those of the author and do not necessarily represent the views of the grant provider or the AANS. This educational activity does not endorse one particular type of instrumentation, nor is it intended to dictate an exclusive course of management. It presents one of numerous recognized methods of clinical practice for consideration by physicians for incorporation into their practices. Variations of practice taking into account the needs of the individual patient, resources, and limitations unique to the institution or type of practice may be appropriate. Disclosure about patient confidentiality, standards of care, or course of management does not imply endorsement or disapproval of products. 

Please Note: It is recognized that the use of non-FDA approved devices is described in some of the published material, but these techniques are often the standard of care and may be of value to the patients we serve

The AANS is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. 

The AANS designates this internet enduring material for a maximum of .25  AMA PRA Category 1 Credit™. Physicians should claim only credit commensurate with the extent of their participation in the activity. 

Term of approval is for three years, beginning from 02/22/2016 until 02/22/2019. 

After completing the activity and successful completion of the test, AANS members will be able to see the CME automatically reflected in your record and you can print a certificate. Non-Members must print a CME certificate and retain it for your records.

Time to complete this activity varies by learner. For this activity you may earn up to .25  AMA PRA Category 1 Credit™.

Copyright© 2016 American Association of Neurological Surgeons. All rights reserved.


Open to view video.
Open to view video.
10 Questions
10 Questions
0.25 AMA PRA Category 1 Credits credits  |  Certificate available
0.25 AMA PRA Category 1 Credits credits  |  Certificate available